Expand renal possibilities for all HD patients
Expanded haemodialysis (HDx) therapy is the next evolution in haemodialysis that brings us a step closer to the natural kidney.1 HDx enabled by Theranova* features an innovative membrane for higher permeability compared to HD and HDF to enable efficient removal of large middle molecules (25 kDa to <60 kDa).2,3,4
Some of these large uraemic toxins have been linked to inflammation, cardiovascular disease and other co-morbidities in dialysis patients.5,6
There is a growing body of evidence showing that HDx can improve key patient reported outcomes
The majority of people on haemodialysis will experience some degree of symptom burden
Self-reported symptom burden is associated with higher mortality, lower quality of life, and depression in individuals' on HD
HDx therapy may improve patient-reported outcomes including: uremic pruritus, restless leg syndrome and recovery time.
Introducing Theranova for Expanding Hemodialysis (HDx) Prof. Claudio Ronco, Italy September 9th 2020
Expanded HD: Exploring the Unmet Need & Medical Evidence Prof. Chris Mclntyre, Ontario, Canada September 21st 2020
HDx therapy delivers meaningful and relevant innovation for dialysis patients
Safety Evidence
HDx therapy enabled by the Theranova dialyser provides superior removal of large middle molecule uraemic toxins compared to conventional HD and HDF while retaining essential proteins and maintaining stable albumin levels.2,3,7
Performance
HDx therapy enabled by the innovative Theranova dialyser with increased nominal pore size, targets the efficient removal of large middle molecule uraemic toxins without the need for a more complex setup than regular HD.1,6
Clinical Effectiveness
HDx therapy addresses pathophysiological responses and clinical outcomes that challenge patients undergoing haemodialysis for treatment of end stage kidney disease.8
Patient-Reported Measures
HDx therapy may improve patient-reported outcomes related to quality of life aspects of kidney disease, including symptom burden, restless legs syndrome criteria, pruritus and dialysis recovery time.4,8,9
Operational Efficiency
With HDx therapy, not only can Theranova provide advanced performance compared to HD and HDF along with clinical and patient-reported benefits but HDx therapy can be prescribed using regular HD workflow and infrastructure.6,10
Economics
While HDx therapy may offer the potential to improve access to care and to help improve the effectiveness and quality of care, HDx therapy may simultaneously offer dialysis service providers and healthcare systems alike the opportunity to reduce the total cost of care.11,12
Baxter's Commitment to You
HDx therapy provides high-performance haemodialysis treatments by targeting the efficient removal of large and conventional middle molecules (500 Da to <60 kDa), many of which have been linked to the development of inflammation, cardiovascular disease and other comorbidities in dialysis patients.1,3,4
The Healthcare Concern
Conventional and large middle molecules effect a range of biological functions including inflammation and cardiovascular risk. The retention of these molecules has been associated with higher mortality in chronic kidney disease patients.6
The Challenge
Traditional high-flux membranes prescribed for use in haemodiafiltration and high-flux haemodialysis treatments have limited capability to remove conventional and large middle molecule uraemic toxins.1,5,6
HDx Therapy Brochure
Here you can find the HDx therapy brochure with more information about prescribing HDx for your haemodialysis patients.
HDx Therapy Specification Sheet
Here you can find the detailed profiles of Theranova dialysers.
Reference Library
Hear from patients, nephrologists, and nurses alike as they share their experience prescribing HDx. Be reassured by the pioneering commitment of Baxter to dialysis patients the world over and learn how Theranova dialysers are made.
Related Products
Important Safety Information
Theranova dialysers are indicated for treatment of chronic and acute renal failure by haemodialysis.
*Do not use Theranova dialysers in HDF or HF mode.
For safe and proper use of this device, please refer to Instructions for Use.
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